290 research outputs found
Concept-Based Approach in Writing Instruction: The Effect of Concept Model
This paper reports the effect of concept model as mediation in writing instruction. Concept in this study refers to the generalizing language in an argumentative essay (e.g. thesis statement, topic sentence, wrap-up sentence and restatement of thesis) since such language constitutes the basic structure of an essay. Based on Ferreira and Lantolf (2008), a five-week experiment was performed, in which “movement from the abstract to the concrete†approach was used. The experiment procedure consisted of four steps: facing problems, producing concept models, revising concept models and applying concept models. But the control group experienced a traditional approach, “movement from the concrete to the abstractâ€. The results manifest the facilitating effect of concept model on knowledge internalization
Inhibition of Protein Tyrosine Phosphatase 1B by Polyphenol Natural Products: Relevant to Diabetes Management
Many biologically active polyphenols have been recognized for their beneficial effects in managing diabetes and their complications. However, the mechanisms behind their functions are poorly understood. As protein-tyrosine phosphatase 1B (PTP1B) has been identified as a target for anti-diabetic agents, the potential inhibitory effects of a dozen structurally diverse polyphenol natural products have been investigated. Among these polyphenols, potent inhibitory activities have been identified for 6 of them with IC50 in micromolar range, while the other polyphenols showed very weak inhibition. A structure-activity relationship (SAR) study and molecular ducking results suggest that both a rigid planar 3-ring backbone and appropriate substitutions of hydroxyl groups benefit the inhibitory activity. The mechanism of inhibition of PTP1B was further investigated by Michaelis-Menten kinetics and the inhibition mode for PTP1B was determined along with the inhibition constant
Comparison of Five Spatio-Temporal Satellite Image Fusion Models over Landscapes with Various Spatial Heterogeneity and Temporal Variation
In recent years, many spatial and temporal satellite image fusion (STIF) methods have been developed to solve the problems of trade-off between spatial and temporal resolution of satellite sensors. This study, for the first time, conducted both scene-level and local-level comparison of five state-of-art STIF methods from four categories over landscapes with various spatial heterogeneity and temporal variation. The five STIF methods include the spatial and temporal adaptive reflectance fusion model (STARFM) and Fit-FC model from the weight function-based category, an unmixing-based data fusion (UBDF) method from the unmixing-based category, the one-pair learning method from the learning-based category, and the Flexible Spatiotemporal DAta Fusion (FSDAF) method from hybrid category. The relationship between the performances of the STIF methods and scene-level and local-level landscape heterogeneity index (LHI) and temporal variation index (TVI) were analyzed. Our results showed that (1) the FSDAF model was most robust regardless of variations in LHI and TVI at both scene level and local level, while it was less computationally efficient than the other models except for one-pair learning; (2) Fit-FC had the highest computing efficiency. It was accurate in predicting reflectance but less accurate than FSDAF and one-pair learning in capturing image structures; (3) One-pair learning had advantages in prediction of large-area land cover change with the capability of preserving image structures. However, it was the least computational efficient model; (4) STARFM was good at predicting phenological change, while it was not suitable for applications of land cover type change; (5) UBDF is not recommended for cases with strong temporal changes or abrupt changes. These findings could provide guidelines for users to select appropriate STIF method for their own applications
Data-driven intelligent computational design for products: Method, techniques, and applications
Data-driven intelligent computational design (DICD) is a research hotspot
emerged under the context of fast-developing artificial intelligence. It
emphasizes on utilizing deep learning algorithms to extract and represent the
design features hidden in historical or fabricated design process data, and
then learn the combination and mapping patterns of these design features for
the purposes of design solution retrieval, generation, optimization,
evaluation, etc. Due to its capability of automatically and efficiently
generating design solutions and thus supporting human-in-the-loop intelligent
and innovative design activities, DICD has drawn the attentions from both
academic and industrial fields. However, as an emerging research subject, there
are still many unexplored issues that limit the development and application of
DICD, such as specific dataset building, engineering design related feature
engineering, systematic methods and techniques for DICD implementation in the
entire product design process, etc. In this regard, a systematic and operable
road map for DICD implementation from full-process perspective is established,
including a general workflow for DICD project planning, an overall framework
for DICD project implementation, the computing mechanisms for DICD
implementation, key enabling technologies for detailed DICD implementation, and
three application scenarios of DICD. The road map reveals the common mechanisms
and calculation principles of existing DICD researches, and thus it can provide
systematic guidance for the possible DICD applications that have not been
explored
An Efficient Public Key Management System: An Application In Vehicular Ad Hoc Networks
The major purpose of Vehicular Ad Hoc Networks (VANETs) is to provide safety-related message access for motorists to react or make a life-critical decision for road safety enhancement. Accessing safety-related information through the use of VANET communications, therefore, must be protected, as motorists may make critical decisions in response to emergency situations in VANETs. If introducing security services into VANETs causes considerable transmission latency or processing delays, this would defeat the purpose of using VANETs to improve road safety. Current research in secure messaging for VANETs appears to focus on employing certificate-based Public Key Cryptosystem (PKC) to support security. The security overhead of such a scheme, however, creates a transmission delay and introduces a time-consuming verification process to VANET communications. This paper proposes an efficient public key management system for VANETs: the Public Key Registry (PKR) system. Not only does this paper demonstrate that the proposed PKR system can maintain security, but it also asserts that it can improve overall performance and scalability at a lower cost, compared to the certificate-based PKC scheme. It is believed that the proposed PKR system will create a new dimension to the key management and verification services for VANETs
Pairwise Confusion for Fine-Grained Visual Classification
Fine-Grained Visual Classification (FGVC) datasets contain small sample
sizes, along with significant intra-class variation and inter-class similarity.
While prior work has addressed intra-class variation using localization and
segmentation techniques, inter-class similarity may also affect feature
learning and reduce classification performance. In this work, we address this
problem using a novel optimization procedure for the end-to-end neural network
training on FGVC tasks. Our procedure, called Pairwise Confusion (PC) reduces
overfitting by intentionally {introducing confusion} in the activations. With
PC regularization, we obtain state-of-the-art performance on six of the most
widely-used FGVC datasets and demonstrate improved localization ability. {PC}
is easy to implement, does not need excessive hyperparameter tuning during
training, and does not add significant overhead during test time.Comment: Camera-Ready version for ECCV 201
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